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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ALDH8A1
All Species:
16.67
Human Site:
T389
Identified Species:
33.33
UniProt:
Q9H2A2
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H2A2
NP_072090.1
487
53401
T389
K
D
E
S
C
C
M
T
E
E
I
F
G
P
V
Chimpanzee
Pan troglodytes
XP_001170111
490
53679
T392
K
D
E
S
C
C
M
T
E
E
I
F
G
P
V
Rhesus Macaque
Macaca mulatta
XP_001101362
515
55911
T417
K
D
E
S
C
C
M
T
E
E
I
F
G
P
V
Dog
Lupus familis
XP_533415
487
53149
K389
K
D
E
S
C
C
M
K
E
E
I
F
G
P
V
Cat
Felis silvestris
Mouse
Mus musculus
Q8BH00
487
53645
T389
K
D
E
S
R
C
M
T
E
E
I
F
G
P
V
Rat
Rattus norvegicus
P13601
501
54541
K398
T
D
E
M
R
I
A
K
E
E
I
F
G
P
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509667
487
53578
Q389
K
D
E
S
S
C
M
Q
E
E
I
F
G
P
V
Chicken
Gallus gallus
P27463
509
55791
K406
T
D
D
M
R
I
A
K
E
E
I
F
G
P
V
Frog
Xenopus laevis
Q6GNL7
902
99964
E804
E
M
F
I
A
K
E
E
S
F
G
P
V
M
I
Zebra Danio
Brachydanio rerio
Q66I21
487
53336
Q389
K
D
S
S
A
L
M
Q
E
E
I
F
G
P
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_509203
506
55370
T404
H
D
A
S
K
V
M
T
D
E
I
F
G
P
V
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q56YU0
501
54342
Q397
T
E
D
M
K
I
Y
Q
D
E
I
F
G
P
V
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92.4
86
87.2
N.A.
89.9
38.3
N.A.
80.6
38.3
23.7
74.1
N.A.
N.A.
N.A.
49.4
N.A.
Protein Similarity:
100
94.2
89.1
95
N.A.
95.4
56.8
N.A.
90.3
55.5
36.5
87.6
N.A.
N.A.
N.A.
67.1
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
93.3
60
N.A.
86.6
53.3
0
73.3
N.A.
N.A.
N.A.
66.6
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
60
N.A.
86.6
60
13.3
73.3
N.A.
N.A.
N.A.
73.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
37.1
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
58.8
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
40
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
60
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
0
17
0
17
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
34
50
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
84
17
0
0
0
0
0
17
0
0
0
0
0
0
% D
% Glu:
9
9
59
0
0
0
9
9
75
92
0
0
0
0
0
% E
% Phe:
0
0
9
0
0
0
0
0
0
9
0
92
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
9
0
92
0
0
% G
% His:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
9
0
25
0
0
0
0
92
0
0
0
9
% I
% Lys:
59
0
0
0
17
9
0
25
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% L
% Met:
0
9
0
25
0
0
67
0
0
0
0
0
0
9
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
9
0
92
0
% P
% Gln:
0
0
0
0
0
0
0
25
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
25
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
9
67
9
0
0
0
9
0
0
0
0
0
0
% S
% Thr:
25
0
0
0
0
0
0
42
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
9
0
0
0
0
0
0
9
0
92
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _